The Mining Play

Global Health Effects on Markets and Mining Stock

No no no. (This is the proper link: Ivermectin | COVID-19 Treatment Guidelines )

There are a clinical trial or two ongoing to see if it works because there was some studies that it worked in a petri dish. However, it appears that to scale that work up, the dosage in humans would have be something like 1000 times the safe dosage. (i.e. it would cure you of COVID but you would be blind, in coma or dead.) It is a dead end.

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Mike,
From your link: Last Updated: February 11, 2021

Ivermectin is not approved by the FDA for the treatment of any viral infection.
Recommendation
There is insufficient evidence for the COVID-19 Treatment Guidelines Panel (the Panel) to recommend either for or against the use of ivermectin for the treatment of COVID-19. Results from adequately powered, well-designed, and well-conducted clinical trials are needed to provide more specific, evidence-based guidance on the role of ivermectin in the treatment of COVID-19.

I like to look for quality of truth and accuracy in a range of distributed information. I see where about 1/3 of the countries in the world are effectively using Ivermectin as a prophylactic and early infection treatment with zinc and antibiotics with good results in reducing death from Covid-19. Inexpicably, there is opposition and a lack of promotion for early therapeutic treatments in the US before hospitalization is required. Unfortunately, this has resulted in far too much censorship and purposeful misinformation put out by government bureaucrats and MSM that can only see yesterday’s science and agendas. There really is a rabbit hole and a great divide in this country that needs to be revealed and healed. Cancel culture and ignorance has cost the country far too much. Is vaccination the universal answer for everyone in reducing deaths from this disease?

I agree we are all at risk, but it’s a relative risk that must be weighed on an individual basis. I can support vaccination while opposing forced vaccination by mandate. Vaccination for diseases such as smallpox with a mortality rate of 30% or Polio with a mortality rate of 23% are easily accepted and warranted. Public health policy that fails to consider the effectiveness of natural immunity will fail to meet its goal of public safety. Covid-19 has a mortality rate of about 1% overall, much higher in the elderly and those with comorbidities, with 80% of deaths occurring in those over 65 years of age. In those under 18, the average mortality rate over the past 3 years for seasonal flu is greater than that for Covid-19 (source CDC). The occurrence needing hospitalization is so low that vaccination does not warrant the mandating of vaccination in this young age group. Coercing a vaccine on a population without considering all the science and updating its data and policies does not govern wisely. The link you provided was last updated in early February. Much progress has occurred since that time. There are actually many studies supporting the safe use of Ivermectin. The FDA/CDC/NIH have put a low priority on conducting gold standard research to support it’s use

Why?

Ivermectin for COVID-19: real-time meta analysis of 64 studies

Covid Analysis, Oct 21, 2021, Version 136

•Meta analysis using the most serious outcome reported shows 67% [53‑76%] and 86% [75‑92%] improvement for early treatment and prophylaxis, with similar results after exclusion based sensitivity analysis (which excludes all of the GMK/BBC team studies), with primary outcomes, and after restriction to peer-reviewed studies orRandomized Controlled Trials.

•Statistically significant improvements are seen for mortality, ventilation, ICU admission, hospitalization, recovery, cases, and viral clearance. 31 studies show statistically significant improvements in isolation.

•Results are very robust — in worst case exclusion sensitivity analysis 53 of 64 studies must be excluded to avoid finding statistically significant efficacy.

•While many treatments have some level of efficacy, they do not replace vaccines and other measures to avoid infection. Only 25% of ivermectin studies show zero events in the treatment arm.

Multiple treatments are typically used in combination, and other treatments could be more effective, including monoclonal antibodies which may be available in countries not recommending ivermectin (sotrovimab, casirivimab/imdevimab, andbamlanivimab/etesevimab).

•Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all variants. All practical, effective, and safe means should be used, including treatments, as supported by Pfizer [Pfizer, TrialSiteNews] . Denying the efficacy of treatments increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage.

•There is evidence of a negative publication bias, and the probability that an ineffective treatment generated results as positive as the 64 studies is estimated to be 1 in 222 billion.

Over 20 countries have adopted ivermectin for COVID-19. The evidence base is much larger and has much lower conflict of interest than typically used to approve drugs.

•All data to reproduce this paper and sources are in the appendix. See [Bryant, Hariyanto, Kory, Lawrie, Nardelli] for other meta analyses with similar results confirming efficacy.

Global Adoption 36%

•There is evidence of a negative publication bias, and the probability that an ineffective treatment generated results as positive as the 64 studies is estimated to be 1 in 222 billion.

Over 20 countries have adopted ivermectin for COVID-19. The evidence base is much larger and has much lower conflict of interest than typically used to approve drugs.

•All data to reproduce this paper and sources are in the appendix. See [Bryant, Hariyanto, Kory, Lawrie, Nardelli] for other meta analyses with similar results confirming efficacy.

https://ivmmeta.com

There is much more on this one site validating the efficacy of using Ivermectin (and other sites if one has a discerning eye for facts) that is constantly updated. FDA’s “Treatment Guidelines Panel” is not staying informed of the facts or just chooses to ignore them. Many researchers have been forced into pre-publication because Journals tend to only support those large Pharmaceuticals that advertise and support publication in their journals. The CDC and FDA have bungled far too much and ignored legitimate data being used elsewhere throughout the globe. Why?

A return to common sense based on science would yield far more success in winning the fight to reduce deaths caused by Covid-19. Restore economic health without resorting to forced mandates. If this disease had the same mortality rates as Smallpox (30%) and Polio (approx. 23% - CDC) people would not be hesitating to receive the vaccine.

this guy is very knowledgeable…even health professionals find his videos helpful. Guys been treating covid patients from day one

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Thanks for posting this, Elrac. Very informative.

Stunning results…game changer? Pfizer Inc. - Pfizer’s Novel COVID-19 Oral Antiviral Treatment Candidate Reduced Risk of Hospitalization or Death by 89% in Interim Analysis of Phase 2/3 EPIC-HR Study

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China is undoubtably the the origin, and largely responsible for the spread, of Covid-19 globally, including the 750 thousand (748,164 as of 11/3/2021 CDC) deaths in the US. China has been the game changer responsible for drastic mandates where China has an overly large economic and political influence. This report from Australia is rather alarming:

Thousands of Australians Protest ‘Unlawful’ Pandemic Bill in Victoria

Bill would give unprecedented pandemic powers to state premier

By Caden Pearson

November 6, 2021 Updated: November 6, 2021

biggersmaller

Thousands of Australians have gathered outside Victoria’s parliament building to protest proposed laws that would see Victoria State Premier Dan Andrews given unprecedented pandemic-related power, as well as mandatory vaccination.

The protesters began to gather around midday, with some chanting “kill the bill,” and with many holding signs expressing their views.

Some of the signs read: “Save our children,” and “Vaxtoria.”

A woman addressed the crowd just after 2 p.m., saying the proposed Andrews government bill was “unlawful” and “needs to be invalidated.”

The protesters pledged to return to hold a similar protest next weekend and march across the city to the governor’s residence.

Victorians have endured some of the longest lockdowns in the world, along with harsh restrictions.

Civic pushback against those restrictions has been met with martial force, erupting in September into days of protests and unrests that saw police officers fire non-lethal rounds at protesters.

The Public Health and Wellbeing (Pandemic Management Bill 2021) is being hurried through parliament and has passed through the lower house.

The laws would give the state premier unprecedented power to declare a pandemic and extend any declared state of emergency for three months.

The current emergency conditions are due to expire in December. Typically, they run for three months and have been extended every three months since first being declared in March 2020.

Traditionally, this power has sat with the chief health officer, but the new bill would hand it over to the premier.

The legislation will require the backing of three out of 11 cross-benchers to pass through the upper house.

The move comes as the state—and the nation—has reached 80 percent vaccination coverage, and has thereby began to lift pandemic restrictions for the fully vaccinated.

About 82 percent of people aged over 12 are fully vaccinated in Victoria.

Best video available on how mRNA vaccines work-very well done!

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Health Mandates, Premature deaths, Inflation, Supply shortages, Border enforcement, Immigration, Worker and productivity shortages. Things are getting messy on many fronts, owing largely to Covid and China’s undue influence on global economies and Supply Chains. Why are things getting so far out of hand? I recently saw a short 42 1/2 minute interview titled “Why the Stock Market Will Be in Trouble” with Steve Forbes. This was given the day before last week’s regional elections. I was intrigued by what he had to say about Monetary Inflation and Marketplace Inflation. Also interesting were the comments concerning constraints on energy supplies and the impact being caused by the transition away from fossil fuels to renewables. I tried to transcribe from about the 19’ mark to the 25’ mark of his interview. I provide the link at the end of his selected comments for anyone that wants to hear Steve Forbe’s interview in it’s entirety. It is as close as I could manage to make it accurate. Some of the points Mr. Forbes brings up about resources needed for a wind farm as opposed to natural gas electrical turbine generation are truly astonishing and disturbing. I especially found the projections for increased mining needed for Lithium, Nickel, Graphite and Cobalt to satisfy the needs of renewable energy sources of great interest. For anyone paying attention, it should be possible to profit from these mining sectors, in addition to gold and silver.

Why the Stock Market Will Be in Trouble
Steve Forbes
(Smart Money Tracker)

Now let’s get to the truth about renewables … This is again something that’s gotta be stopped, because otherwise it’s going to drain a lot of resources ultimately impact the value of equities. Let’s go to the truth. If you take him 100 MW gas turbine, natural gas turbine, that turbine is about the size of a residential house and can provide electricity for about 75,000 homes. So remember that, turbine, natural gas, size of a house for 75,000 customers… Now, the equivalent wind farm to provide that kind of electricity for 75,000 homes reliably would be 10 square miles versus the size of a residential house. It will require 20 turbines. Each bigger than the Washington Monument. It will require 50,000 tons of concrete, 30,000 tons of iron ore, 900 tons of non recyclable plastics … and of course with energy, as we’ve all seen with Texas and elsewhere, you need, if you don’t have storage you’re going to be in trouble. So if you want proper storage for 24/7 reliable electricity in that wind farm, that’ll take, get this, 10,000 tons of Tesla class batteries. That’s just 10,000 tons for one wind farm . Multiply that by a couple of 1000 here, and thousands more around the world. Do you see the utter ridiculous and destructiveness of this push for so-called renewable energies? Just look what this would do for mining. These things require a lot of minerals. Mines that are not easy to sync. They take up a lot of earth. For lithium, they’d have to increase the output of lithium 44 fold, Nickel 20 fold, graphite 25 fold. Massive increase in cobalt … oh, guess who controls cobalt in in in in the world? In terms of the refining cobalt, China! So this thing just doesn’t, this thing just doesn’t work. Nonetheless, nonetheless they’re going full bore on the so-called renewables. Which is going to be a real disaster if they’re not stopped, in terms of what it does to the future of this economy.

On the terms of regulations already mentioned that they’re doing on the energy side, they’re doing it on the union side. Just going to be crushing small businesses, and also we’ve already seen supply chains. What happened with those of COVID lockdowns is that it made people begin to realize just how sophisticated, utterly complicated, supply chains are in the modern world. You just don’t turn them on and off like a faucet or a light switch … And so let’s look at what’s happening. Let’s take California, the ports there in Long Beach, in Los Angeles … That’s where 40% of our imports come from, critical parts in the life, lots of Christmas toys sitting out in that harbor because they can’t unload them now. One of the big reasons why they can’t unload them is that Los Angeles and Long Beach have a rule … that is you can’t stack empty containers. Now normally what happens is a truck delivers a container on for export. They then picked up a container with the imports and go about delivering them. Well, because of the disruptions of COVID, we didn’t get a lot of exports as we normally would … And then they ended up with a lot of empty, empty containers. Where do you store empty containers?

Now, normally in a port you’re just stacking one on top of the other, but in Los Angeles and Long Beach you can’t. If they’re above two, you will find you’re in trouble. You’re committing a crime. Now a fella named Ryan Peterson who heads up a great new freight forwarding company, came up with a solution. Long Beach in Los Angeles should temporarily waive that anti stacking rule and allow the containers to be stacked. So that way the trucks can then have the space since they’re not storing these empty containers. The trucks can unload those empty containers, and you get to take filled up containers from those ships and start delivering them. Unfortunately, when Peterson wrote up a tweet that became a tweet storm. The city of Oakland, ah not Oakland, but Long Beach said OK. You can instead of restricting the stacking to two, you can do 4. Well, that’s a start. Los Angeles still is not doing it, so those kinds of basic changes allow temporarily stacking.

Peterson also has other ideas, such as temporary storage yard of 500 acres within 100 miles of those two ports, temporary, to store empty containers. Make sure we get those containers moving. And yet, what, what is the government doing up there to the applause of the Biden administration? They’re now imposing fines on shippers, further delay. They helped cause the delays but they’re gonna end up putting on fines! What’s that going to do? That’s going to hurt. That’s going to put out of business some of the smaller shippers with those kinds of massive fines. I guess as well, we’re going to pay the fines, you the consumer in the way of higher prices.

Trucking Regulations … Trucking regulations, a lot of unnecessary regulations there, or at least should be suspended allowing truckers to drive an extra hour a day, at the proper pay. Allow 18 year olds to go across state lines driving a truck. Silly kind of regulations, temporarily, at least temporarily waive them so we get these bottlenecks up and moving again fortunately. Florida and Texas may have made clear that their ports are open 24/7 and even though it’s more expensive to take these container ships to Florida and Texas, it’s not going to be so expensive giving them massive cost of this sitting out in the harbor and the dead of water not able to move those goods and therefore not getting the shipping fees you need to stay in business. So that’ll help a little bit, and by the way Florida and Texas, they say their ports will be open 24/7. Now in Long Beach and Los Angeles, the Biden Administration, we’re going to have them operate 24/7. Well, only one terminal out there is operating 24/7. The rest are not, and oh, that one little terminal is only doing it four days a week.

Why the Stock Market Will Be in Trouble | Steve Forbes - YouTube

A really well done review of Ivermectin studies. To make a very long story short, this deworming drug likely has a small benefit for surviving COVID…if you have worms. Note that in practice, the drug is likely harmful since people that take it tend to alter their behavior thinking that they are protected. The drug works of course by killing worms. Having worms makes one more likely to die of COVID. A large percentage of the populations in the tropical regions do indeed have worms.

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Mike,
I’ll refer you to look back to the information at what the rest of the world has researched. It is ZINC that stops the replication of the virus inside the cytoplasm of the cell. A zinc supplement will circulate in the blood, but does not easily enter through the cell membrane. Ivermectin (and other safe repurposed drugs that are used off label) act as an ionosphore for zinc where it can stop replication of the virus before it replicates exponentially in the very early stages of infection. Ionophores are lipid-soluble entities that transport ions across the cell membrane. It is not effective for later stage hospitalized patients.

Global Adoption 36%
[/quote]

Looks like what was feared to happen has indeed happened. A more dangerous variant than Delta is starting to spread/overtake the other variants in Africa. It will likely be much better at evading vaccines than existing variants as well. My news feeds are full of stories about this new variant. The mutations on it are being described as “horrible”. Pretty sure it will make 2022 as crappy as 2021 was. The WHO will likely be giving its own Greek letter tomorrow. (Probably “NU” Variant.) Stay tuned! Covid: New heavily mutated variant B.1.1.529 in South Africa raises concern - BBC News

The usual knee-jerk reaction to a new variant is being felt in the markets this morning. Oil noticeably dropped 4-5% largely due to fear of more mandates, lockdowns and fear mongering reports of a rapidly spreading variant. The forum thread is aptly titled “Global Health Effects on Markets and Mining Stocks” and this virus is causing very widespread stress in many unanticipated areas. What is the transmissivity and morbidly of this virus? It is unknown whether vaccines will be effective to this new variant presently known as B.1.1.529. Clearly, in general, antibodies are present in the blood of most Americans. Breakthrough reinfections are infrequent occurring in about 1 in 5,000 so the vaccines are working as expected. Are universal boosters for all age groups really warranted? Why aren’t better prophylactic and more economical antivirals being used instead of expensive EAU vaccines to keep admissions to hospitals rare?

“Breakthrough reinfections are infrequent occurring in about 1 in 5,000 so the vaccines are working as expected.”

72% in S. Africa have already been infected by the previous variants of COVID per best estimates yet the new variant shows signs it is already running rampant. It is either ridiculously transmissive or going crazy with break through/repeat infections. It is so different with such a sudden huge mutated spike protein that perhaps it more correctly should be known as COVID-21?

They can already say the REGEN-COV and Eli Lily won’t work but AstraZeneca probably will. The mRNA vaccines don’t target the mutated spike protein but they are not sure how they will fare. Some of the spread has already been associated with the Pfizer vaccinated. I will guess we will see the usefulness of those vaccines do much more poorly than with Delta but not be completely useless especially with a Moderna booster.

It will soon be obvious that it has probably spread all over the world already since they are having difficulty testing for it and it surely with cause more market waves. Perhaps the anti-viral drugs will save the day in 2022?

Edit: It is now officially known as the “Omicron” variant.

Derivation of Names for the Variants

The following link is a prequel to a year-end review by a controversial Cornell University Organic Chemistry professor. Interspersed with personal insights from his 40 years of investing, I think you’ll find it useful. A more appropriate title could have been, “the Politicisation of Science, a Chronic Problem” or maybe “An Age of Narratives”.

The professor does a great interview. How can we have a rational discourse when you can cite “facts” that support either of two sides, both of which claim crediblity, and both sides may be lying? David Callum will definitely give you a perspective that makes you think!

What happens when only one side of the narrative is generally presented in the MSM? Professor Collum discusses some controversial topics later in the interview such as “Planned Obsolescence”, “Great Decades & Now” and the very timely topic, “Understanding China”. China has an aging population problem. China’s military could give rise to multiple Black Swan events.

One of the last scientists to leave Wuhan was an Aussie defending the CCP. We are watching the Aussies respond to the virus in the most surreal ways. Put those two ideas together into one narrative.

To lighten up, David interjects a lot of humor into his observations and opinions.
Be prepared to be entertained and enlightened as he covers many of the world’s problems.

(David Collum: The Digital World and Rise of Authoritarianism - YouTube)

Selected Time Marks

The preliminary data coming out on Omicron doesn’t look good. Here are some examples:

  1. 580 people in South Africa’s Gauteng province were hospitalized with COVID-19 last week, up 330% from 2 weeks ago. (This refutes an earlier hope that perhaps Omicron would be less virulent.)

  2. 13 Omicron variant cases now confirmed from 61 #COVID19 cases among ~600 passengers on two flights from South Africa to Amsterdam

  3. Scotland reports 6 cases of Omicron, including people with no travel history, indicating community transmission

  4. Omicron likely emerged via an HIV infected individual weeks/months ago in an area with no surveillance.

  5. Omicron may have a defect in its own proofreading/error correction functions suggesting an ability to further mutate rapidly at a pace far beyond what was thought possible for Coronaviruses.

  6. Omicron is very easily infecting individuals who have had COVID before. Cases of vaccinated individuals having the Omicron variant have already been documented.

  7. Omicron’s rapid spread likely due to a higher RO value that Delta plus its ability to reinfect individuals with prior COVID.

  8. Israel is now reporting community transmission of Omicron from a cardiologist with 3 doses to another cardiologist with 3 doses of vaccine.

Head of Moderna says their vaccine is no match for the Omicron. The implications of this are obvious. Plan accordingly.

“There is no world, I think, where (the effectiveness) is the same level . . . we had with Delta,” Moderna CEO Bancel told the Financial Times in an interview.

“I think it’s going to be a material drop. I just don’t know how much because we need to wait for the data. But all the scientists I’ve talked to … are like ‘this is not going to be good’,” Bancel said.

While vaccines may be less effective against this variant and the variant may be more contagious, we may also find out that it is less debilitating.

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3 vaccine shots now and still not safe. Here in Michigan, all the hospitals are at capacity and beyond with just the Delta variant. I’m thinking that we will likely see an improvement for a time for the later part of the Winter after Christmas into Spring until the next variant has a chance to spread.

Vaccines still might make the difference between from just having a hospital stay and death-that seems probable.

I do note that a one or two S. African officials have made some comments suggesting that Omicron might be milder form of COVID but there is zero indication of that in that actual data that I’ve seen. (In fact, it shows the opposite.) I’m thinking it is more a case of wish thinking or more of a political statements than reality.

Even if it turns out to be a less severe strain, it would likely make up for it in its ability to infect more people such as the previously infected with other strains.